- Umifenovir hydrochloride monohydrate. PubChem CID. 131410. Structure. Find Similar Structures. Molecular Formula. C22H28BrClN2O4S. Synonyms. UNII-YFE0A1FOSX.
- Umifenovir (Arbidol®) is an indole derivative first marketed in 1993 for the prophylactic treatment of infections caused by influenza A and B viruses . Produced by Pharmstandard, it is still currently used in Russia and China to treat influenza infections . Umifenovir is marketed in 50 and 100 mg capsules, being administered orally.
- 131707-25- - KCFYEAOKVJSACF-UHFFFAOYSA-N - Umifenovir [INN] - Similar structures search, synonyms, formulas, resource links, and other chemical information.
- Umifenovir (Arbidol) Viral surface protein for binding to host cell receptor ACE2. Used in China and Russia. Immunotherapies. Drug Name. Manufacturer. Potential Mechanism of Action. Other information. Anti-SARS-CoV-2 polyclonal hyperimmune globulin. Takeda
- Umifenovir showed an effect in an in vitro study on COVID-19 (Table 2). In an RCT comparing a combination of umifenovir and lopinavir/ritonavir with standard treatment, the group receiving the treatment with umifenovir did not show better outcome than the control group in terms of clinical deterioration or viral clearance (Table 3).
- Arbidol (Umifenovir) Arbidol is an FDA approved drug for Influenza. Arbidol is an indole based antiviral/host-targeting agent. ... A 2D chemical structure search is provided in addition to a 3D superposition feature that superposes a drug with ligands already known to be found in the experimentally determined protein-ligand complexes.
- This review provides a pharmacological approach to combat Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) based on two comprehensive denominations which could be specifically intended for viral replication process by either inhibiting
- Influenza A virus subtype H5N1 හෝ A(H5N1) එසේත් නැත්නම් සරළව් සරලව H5N1 හැඳින්වෙන්නේ ...
- We report new carboanalogs of umifenovir - regioisomeric derivatives of ethyl 5-hydroxy-(trans-2-phenylcyclopropyl)-1Н-indole-3-carboxylate. The inhibition of HIV replication by umifenovir and its carboanalogs at micromolar concentration range has been demonstrated for the first time.
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Umifenovir. Umifenovir is a broad-spectrum antiviral approved in Russia and China for the prophylaxis and treatment of human influenza A and B infections (Boriskin et al, 2008). Its antiviral mechanism of action is thought to be related to an impaired virus-mediated membrane fusion that is essential for viral entry.viral structure and epidemiology SARS-CoV-2 crossed the animal-human barrier coming from bats in China. It is a single-strand positive-sense RNA virus that is composed of four main structural proteins: spikes (S), small envelope, membrane glycoproteins and nucleocapsid protein. 3 Protein S facilitates the binding of the virus to the ACE2 ...Umifenovir. Umifenovir (Arbidol) is a broad-spectrum antiviral that inhibits viral entry by blocking membrane fusion. In viruses that use clathrin-mediated endocytosis as a means of host cell entry, umifenovir interferes with this process by inhibiting membrane scission.
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